Dark Fermentation

A novel mechanism contacts the broth with head space gas.
Variable mass transfer >400/h ensures efficient gas delivery to the cells throughout the broth volume.
Pressurisation of the bioreactor increases gas solubility (>10 BAR).
Partial vacuum for volatiles recovery.

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Broth 'Milking'

Genetic engineering breakthroughs have allowed us to use microbes to sustainably produce valuable compounds. However, extracting these products (synthate) from the liquid they are grown in (broth) has been a major challenge.

The Horizon Bioreactor solves this problem by continuously and efficiently recovering these secreted metabolites from the broth (Extractive Fermentation). This innovative technology minimizes the negative impact of product build-up, which can hinder production.

Extractive Fermentation

Extraction solvent overlays or underlays enable efficient synthate recovery.
Emulsification is avoided through continual coalescence.
A discrete coalescing zone allows phase separation
Options for Solid extractants (e.g. affinity & ion exchange).

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Photosynthetic microbes

Engineered microalgae and cyanobacteria are seen as promising tools for creating carbon negative commodities. 

These microorganisms are naturally adept at photosynthesis, using light and carbon dioxide (CO2) to grow. 

Using synthetic biology toolkits, the creation of strains optimized for the sustainable production of specific commodities and CO2 fixation is now a reality.

Photo Fermentation

Photons from concentrated sources are delivered at each end into the photobioreactor using interchangeable high intensity light sources.
Variable wavelength spectra.
An optical system distributes light throughout the broth volumes with minimum path lengths of 40mm.
Operation at pressure or partial vacuum.

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Extractive Photo-Fermentation

Extraction solvent overlays or underlays enable efficient synthate recovery.
A discrete coalescing zone allows phase separation
Options for Solid extractants (e.g. affinity & ion exchange).

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Extractant examples

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